Overpriced and hard to come by right now.
Ruger makes the blackhawk, great gun and can shoot hot loads. Available in 44 magnum or 45 colt.
Taurus makes a nice 44 magnum in the tracker series. Cons, well it's a Taurus. Some people look down on this company but they do make good guns, generally, life time warranty. Customer service sucks sometimes but they will fix just about anything wrong with the gun. Even if it's the owners fault.
Colt still makes the 45.Cons, Pricey, twice as much as Taurus or Ruger. Pros, it's a colt.
I'm sure there are others, but those are off the top of my head.